2. Kemenkes RI. Profil Kesehatan Indonesia. 2021.
3. Dinkes Jatim. Profil Kesehatan Jawa Timur. 2021;
4. BPS Kota Kediri. Kota Kediri dalam Angka. Kota Kediri Dalam Angka [Internet]. 2021;1–68. Available from: https://kedirikota.bps.go.id/
5. Prasetyorini T, Fajrunni’mah R, Yasyavia Hatifah I, Karningsih K. Hubungan Antara Lama Penggunaan Kontrasepsi Suntik Depo Medroxy Progesteron Acetate (DMPA) dengan Kadar Kolesterol Total pada Akseptor KB. Muhammadiyah J Midwifery [Internet]. 2021;1(2):37. Available from: https://jurnal.umj.ac.id/index.php/MyJM/article/view/7320
6. Shufelt C, Levee A. Hormonal Contraception in Women with Hypertension. JAMA - J Am Med Assoc [Internet]. 2020;324(14):1451–2. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528006/
7. Sitinjak HL. Perbandingan Kadar Kolesterol Total dan HDL Antara Akseptor KB Pil Kombinasi dan DMPA. Indones J Kebidanan [Internet]. 2019;3(1):1. Available from: https://ejr.stikesmuhkudus.ac.id/index.php/ijb/article/download/587/406
8. Wulandari PC, Surati. Overview of Cholesterol Levels in Injection Contraception Acceptors. 2019;01(02):59–65. Available from: https://ejournal.poltekkes-smg.ac.id/ojs/index.php/JLM/article/view/5448/1422
9. Runiari N, Prawerti WNM, Made R. Lama Pemakaian Kontrasepsi Suntik Depo Medroksi Progesteron Asetat dengan Kadar Kolesterol pada Akseptor KB. J Gema Keperawatan [Internet]. 2019;93–106. Available from: http://ejournal.poltekkes-denpasar.ac.id/index.php/JGK/article/view/892/289
10. Priyo Hastono S, Tataan G, Gedong Tataan K. Indeks Masa Tubuh, Usia dan Peningkatan Kolesterol Total. J Kesehat Metro Sai Wawai [Internet]. 2020;13(1):44–50. Available from: https://ejurnal.poltekkes-tjk.ac.id/index.php/JKM/article/view/1471
11. Lainsamputty F, Gerungan N. Correlation of Lifestyle and Stress in Patients with Hypercholesterolemia. J Ilm Kesehat Sandi Husada [Internet]. 2022;11:138–46. Available from: https://media.neliti.com/media/publications/467732-the-correlation-between-lifestyle-and-st-2f9e1efe.pdf
12. Perol S, Hugon-Rodin J, Plu-Bureau G. Hypertension and contraception. Press Medicale [Internet]. 2019;48(11P1):1269–83. Available from: https://doi.org/10.1016/j.lpm.2019.07.033
13. Lestari EP. Penerapan Therapeutic Lifestyle Change (TLC) Dalam Mengendalikan Kadar Kolesterol Pada Keluarga Dengan Klien Jantung Koroner. Univ Muhammadiyah Magelang [Internet]. 2020;4–11. Available from: http://eprintslib.ummgl.ac.id/2415/
14. Benge ME, Mbulang YKA, Naja FRR. Pengaruh Pemberian Ekstrak Etanol Daun Afrika (Vernonia amygdalina. Del) terhadap Kadar LDL Serum Tikus Hiperkolesterolemia. 2020;3(April):1–6. Available from: https://media.neliti.com/media/publications/316273-pengaruh-pemberian-ekstrak-etanol-daun-a-039f8d6e.pdf
15. Fajar RI, Wrasiati LP, Suhendra L. Kandungan Senyawa Flavonoid Dan Aktivitas Antioksidan Ekstrak Teh Hijau pada Perlakuan Suhu Awal dan Lama Penyeduhan. J Rekayasa Dan Manaj Agroindustri [Internet]. 2018;6(3):196. Available from: https://ojs.unud.ac.id/index.php/jtip/article/view/42653
16. Fazdria F. Efektivitas Teh Hijau dan Sari Kacang Hijau dalam Menurunkan Kadar Kolesterol Total pada Pengguna Kontrasepsi Suntik Progestin. J Kebidanan Malahayati [Internet]. 2021;7(3):376–82. Available from: http://ejurnalmalahayati.ac.id/index.php/kebidanan/article/view/4435
17. Gita Susanti. Aktivitas Ekstrak Daun Kelor (Moringa Oleifera) Terhadap Kadar Kolesterol Tikus Jantan Sprague Dawley. J Kesehat J Ilm Multi Sci [Internet]. 2020;10(01):08–13. Available from: https://jurnal.stik-sitikhadijah.ac.id/index.php/multiscience/article/view/301
18. Marumata CV, Woda RR, Artawan M. Pengaruh Pemberian Jus Daun Kelor (Moringa Oleifera Lam) terhadap Kadar Kolesterol Total Orang Dewasa Hiperkolesterolemia di Wilayah Kerja Puskesmas Oebobo Kota Kupang. Cendana Med J [Internet]. 2019;17(2):325–34. Available from: https://ejurnal.undana.ac.id/index.php/CMJ/article/view/1806
19. Rani KC. Kandungan Nutrisi Tanaman Kelor. Vol. 44, Fakultas Farmasi Universitas Surabaya. 2019. 1689–1699 p.
20. Waode F, Sari, Suwondo A, Arwani. A Literature Review of Effect of Moringa Oleifera Leaf Extract Toward Lipid Profile Level in Hyperlipidemia Patients. Int J Nurs Heal Serv [Internet]. 2022;5(3):294–303. Available from: https://ijnhs.net/index.php/ijnhs/article/view/581
21. Nesyana N, Ulfiah A, Arifin AF, Pratiwi R, Gayatri SW. Efektifitas Pemberian Ekstrak Daun Kelor terhadap Kadar Kolesterol Darah pada Hewan Coba Mencit. UMI Med J [Internet]. 2020;5(1):28–37. Available from: https://jurnal.fk.umi.ac.id/index.php/umimedicaljournal/article/view/86
22. Saleem A, Saleem M, Akhtar MF, Baig MMFA, Rasul A. HPLC analysis, cytotoxicity, and safety study of Moringa oleifera Lam. (wild type) leaf extract. J Food Biochem [Internet]. 2020;44(10):1–14. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13400
23. Talli R, Yuliana B, Fitrianingsih J. Formulasi Kapsul Kombinasi Kacang Hijau (Vigna radiata) dan Daun Kelor (Moringa aloefera) dan Pengaruhnya Terhadap Kadar Hemoglobin Ibu Hamil. Semin Nas Kesehat Masy [Internet]. 2020;1(5):190–7. Available from: https://conference.upnvj.ac.id/index.php/semnashmkm2020/article/view/1061
24. Denta AO, Fauziyah E. Serbuk Daun Kelor Efektif Menurunkan Kadar Glukosa Darah dan Kadar Kolesterol pada Individu Obese. Wiraraja Med J Kesehat [Internet]. 2022;12(1):10–6. Available from: https://ejournalwiraraja.com/index.php/FIK/article/view/1712%0Ahttps://ejournalwiraraja.com/index.php/FIK/article/download/1712/1359
25. Gomes GS, Bidura IGNG, Budaarsa K, Partama IBG. Supplementation of Moringa oleifera Leaf Flour in Diet to Increase Growth Performance and Reduce Cholesterol Content in Meat of East Timor Local Pigs. J Biol Chem Res [Internet]. 2019;36(2):61–8. Available from: https://www.researchgate.net/publication/342672746%0ASupplementation
26. Utama RD. Kolesterol dan Penanganannya. 2021. 1–29 p.
27. Back M, Yurdagul A, Tabas I, Oorni K, Kovanen PT. Inflammation and its Resolution in Atherosclerosis: Mediators and Therapeutic Opportunities. Nat Rev Cardiol [Internet]. 2019;16(7):389–406. Available from: https://doi.org/10.1038/s41569-019-0169-2
28. Affandi B, Andriaansz G, Gunardi ER, Koesno H. Buku Panduan Praktis Pelayanan Kontrasepsi. 2014.
29. Soliman GA. Dietary cholesterol and the lack of evidence in cardiovascular disease. Nutrients [Internet]. 2018;10(6):1–14. Available from: https://doi.org/10.3390/nu10060780
30. Hamna Vonny Lasanuddin, Rosmin Ilham, Rianti P. Umani. Hubungan Pola Makan Dengan Peningkatan Kadar Kolesterol Lansia Di Desa Tenggela Kecamatan Tilango. J Ilmu Kedokt dan Kesehat Indones [Internet]. 2022;2(1):22–34. Available from: https://doi.org/10.55606/jikki.v2i1.566
31. Abdalla HAM, Ali M, Amar MH, Chen L, Wang QF. Characterization of Phytochemical and Nutrient Compounds from the Leaves and Seeds of Moringa oleifera and Moringa peregrina. Horticulturae [Internet]. 2022;8(11):1–18. Available from: https://www.mdpi.com/2311-7524/8/11/1081
32. Darmawan W, Kurnaesih E, Multazam A. Pengaruh Pemberian Kapsul Daun Kelor (Moringa oleifera) terhadap Penurunan Kadar Kolesterol pada Ibu Menopause di Wilayah Kerja Puskesmas Tamamaung. Mitra Sehat [Internet]. 2018;VIII(November):389–99. Available from: https://journal.stikmakassar.com/a/article/download/198/105
33. Tjong A, Assa YA, Purwanto DS. Kandungan Antioksidan Pada Daun Kelor (Moringa Oleifera) dan Potensi Sebagai Penurun Kadar Kolesterol Darah. J e-Biomedik [Internet]. 2021;9(2):248–54. Available from: https://ejournal.unsrat.ac.id/index.php/ebiomedik
34. Adriana V, Khidri Alwi M, Syam A. Pengaruh Pemberian Tepung Daun Kelor (Moringa oleifera) terhadap Profil Lipid pada Penderita Prediabetes di Wilayah Kerja Puskesmas Samata Kabupaten Gowa. J Ilm Kesehat Diagnosis [Internet]. 2019;13:2302–531. Available from: https://jurnal.stikesnh.ac.id/index.php/jikd/article/view/96
35. Sharmin F, Sarker MSK, Sarker NR, Faruque S. Dietary Effect of Moringa oleifera on Native Laying Hens’ Egg Quality, Cholesterol and Fatty-acid Profile. Ital J Anim Sci [Internet]. 2021;20(1):1544–53. Available from: https://doi.org/10.1080/1828051X.2021.1987846
36. Bidura I, Partama IBG, Utami IAP, Candrawati D, Puspani E, Suasta IM, et al. Effect of Moringa oleifera leaf Powder in Diets on Laying Hens Performance, β-carotene, Cholesterol, and Minerals Contents in Egg Yolk. IOP Conf Ser Mater Sci Eng [Internet]. 2020;823(1). Available from: https://iopscience.iop.org/article/10.1088/1757-899X/823/1/012006/pdf
37. Doumandji A, Saidi YR. Anticholesterolemic Activity of Moringa oleifera leaves Methanolic Extract in Triton X-100 induced Hypercholesterolemic Mice. Soc Alger Nutr [Internet]. 2023;12:31–7. Available from: https://www.asjp.cerist.dz/en/downArticle/8/12/1/229141
38. Al Rahmad AH. Pengaruh Pemberian Konseling Gizi terhadap Penurunan Kadar Kolesterol Darah. J Kesehat [Internet]. 2018;9(2):241–7. Available from: http://ejurnal.poltekkes-tjk.ac.id/index.php/JK
39. Indriyana P, Tahlil T, Mudatsir. Pengaruh Therapeutic Lifestyle Change Terhadap Pengaturan Diet, Aktivitas Fisik, Dan Kadar Kolesterol Total Pasien Hiperkolesterolemia Di Puskesmas. J Ilmu Keperawatan [Internet]. 2018;6(1):112–25. Available from: https://jurnal.usk.ac.id/JIK/article/view/13432/10228
40. Ma ZF, Ahmad J, Zhang H, Khan I, Muhammad S. Evaluation of Phytochemical and Medicinal Properties of Moringa (Moringa oleifera) as a Potential Functional Food. South African J Bot [Internet]. 2020;129:40–6. Available from: https://doi.org/10.1016/j.sajb.2018.12.002
41. Babar H, Rizwan B, Babar A, Nazia H, Noreen S, Naeem N, et al. Therapeutic Effect of Moringa Oleifera: A Review. Pakistan Biomed J [Internet]. 2022;5(2):10–3. Available from: https://doi.org/10.54393/pbmj.v5i2.161
42. Umar A, Abubakar MI. Assessment of Medicinal Benefits of Moringa oleifera and its Influence on the Health Outcomes of Poor Communities in Zaria, Nigeria. EC Clin Med Case Reports [Internet]. 2022;5(2):02–12. Available from: https://www.researchgate.net/publication/358242146
43. Simeon JO, Tosin JO, Samuel Sunday Agboola, Adekunle AT, Emmanuel AO, John OA, et al. Investigating Clinical Potential of Moringa oleifera on the c Cholesterol, BMI and Blood Triglyceride Level in HIV/AIDs Patient on Antiretroviral Combination Regimen. J Pharm Sci Res [Internet]. 2023;15(5):1101–8. Available from: at: https://www.researchgate.net/publication/371411707
44. Yuan T, Wen X-Y, Chen Y, Deng Y, Li H-Z, Huang Y. Study on the Hypolipidemic Effect of Moringa oleifera Seeds Based on Zebrafish Hyperlipidemia Model. Asian Plant Res J [Internet]. 2022;10(1):65–70. Available from: http://eparchives.uk/47/1/184-Article Text-317-1-10-20221031.pdf
45. Atufe G, Oweh OT, Avidime OM, Awhin EP, Nurudeen QO. Ameliorative Activities and Safety Of Moringa Oleifera Oil and Nigella Sativa Oil on Diet‑induced Hyperlipidemic Male Wistar Rats. Niger J Exp Clin Biosci [Internet]. 2022;10(1):24–8. Available from: https://www.njecbonline.org/article.asp?issn=2348-053X;year=2022;volume=10;issue=1;spage=24;epage=28;aulast=Atufe;type=0
46. Alqurashi R, Alholaibi M. Polyphenols from Moringa Oleifera and Mulberry Exhibit Anti-Obesity and Anti-Hyperlipidemic Effects in Rats Fed a High-Fat Diet. Curr Top Nutraceutical Res [Internet]. 2023;21(1):102–8. Available from: doi: https://doi.org/10.37290/ctnr2641-452X.21:102–108
47. Wahyu S, Arsal ASF, Indah Chintya Maharani. Efektivitas Ekstrak Daun Kelor ( Moringa Oleifera) terhadap Penurunan Kadar Kolesterol Total pada Tikus Putih (Rattus Novergicus). Green Med J [Internet]. 2019;1(1):97–110. Available from: https://greenmedicaljournal.umi.ac.id/index.php/gmj/article/view/24
48. Yurtseven S, Jalil B. The Effect of Moringa Oleifera Leaf and Canola Seed Powder on Fattening, Laying Performance, Blood Plasma Constituents, and Microbiota in Japanese Quails. Rev Bras Cienc Avic [Internet]. 2023;25(2). Available from: http://dx.doi.org/10.1590/1806-9061-2022-1710
- Abstract viewed - 603 times
- PDF downloaded - 748 times
Downloads
Affiliations
Nilna Hidayatul Husna
Prodi Kebidanan, Politeknik Kesehatan Kemenkes Malang
Finta Isti Kundarti
Prodi Kebidanan, Politeknik Kesehatan Kemenkes Malang
Lumastari Ajeng Wijayanti
Prodi Kebidanan, Politeknik Kesehatan Kemenkes Malang
Ira Titisari
Prodi Kebidanan, Politeknik Kesehatan Kemenkes Malang
How to Cite
Pengaruh Pemberian Ekstrak Daun Kelor (Moringa oleifera) terhadap Kadar Kolesterol pada Akseptor KB Suntik 3 Bulan di Kelurahan Mojoroto Kecamatan Mojoroto Kota Kediri
Vol 14 No 2 (2023): Jurnal Kesehatan Terpadu (Integrated Health Journal) November 2023
Submitted: Aug 8, 2023
Published: Feb 29, 2024
Abstract
Family planning acceptance in Indonesia is high and injectable contraceptives have the highest prevalence. Long-term use of hormonal contraceptives causes changes in lipid metabolism. Moringa has the activity of lowering cholesterol levels. The purpose of this study was to determine the effect of moringa leaf extract (Moringa oleifera) on cholesterol levels. This research method uses a quasy experiment with a sample of 66 respondents consisting of 33 intervention group respondents who were given moringa leaf extract for 28 days and 33 control group respondents) with simple random sampling technique. Data analysis using t test. The results of the paired t test on cholesterol levels in the intervention group showed significant results, namely p value 0.000. The paired t test results on cholesterol levels in the control group showed insignificant results, namely p value 0.532. The results of the independent sample test on cholesterol levels in both groups showed a significant p value of 0.000. Cholesterol levels decreased after giving moringa leaf extract to 3-month injectable birth control acceptors. Health workers can motivate people to utilize moringa plants as a treatment in lowering cholesterol levels.